BREXA Brexa (Silymarin) is a novel medication which has been used for the treatment of different diseases such as Liver Cirrhosis, Hepatitis and Hepatic, Prostate Diseases, Lungs Diseases and Gallbladder Disorders. Brexa contains hepatoprotectant and antioxidant properties which help by scavenging free radicals and increasing the glutathione concentrations, so that it can be used in hepatitis and hepatic cirrhosis treatment. Brexa can also alleviate hepatocyte membrane and thus prevent the xenobiotics from going into the cell via enterohepatic circulation. It can slightly bind to the iron and inhibit human hepatocyte glutathione reduction. Brexa modulate the immune system, and enhances the IFN-γ, IL-4 and IL-10 secretion in cultures containing lymphocytes. Its anti-neoplastic effects are related to the pro-angiogenic factors and growth inhibition, induction of endothelial cells apoptosis through a p53-dependent pathway involving Bcl-2/Bax, cytochrome C release, Apaf-1, and activation of caspase-3 and PARP.                                             MECHANISMS OF ACTION   Brexa increases the regenerative ability of the liver cells by enhancing the synthesis of DNA and RNA, as Brexa has a steroid structure; Altering the structure of the hepatocyte external membrane, that

CHARTING THE FUTURE…A LEGACY OF STRENGTH AND TRUST! Leotetra Healthcare Limited Marks a Decade of Excellence with a Grand Sales Review Conference and Award Night from 9th to 14th February at Porto Golf Hotel, Bompai, Kano State. LEOTETRA Healthcare Limited recently celebrated a decade of groundbreaking achievements with a spectacular General Sales Review Conference, 10-Year Anniversary, and Award Night, a milestone event that reflected on past successes, set the stage for future growth, and honored outstanding contributors to the company’s journey. The event commenced with the General Sales Review Conference, where team members, sales leaders, and stakeholders gathered to analyze the company’s market performance over the past year. A special documentary showcased the brand’s evolution, highlighting key milestones, challenges overcome, and the unwavering commitment to excellence, trust, strength, and values that have defined the company for the past decade. The grand event culminated in a dazzling All White Award Night where the GCEO, Prince Ade’ Adeoba, delivered a powerful keynote address, highlighting the company’s journey from its humble beginnings to becoming a force to be reckoned with in the pharmaceutical